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years ago published a groundbreaking and taboo
2019-06-11
5 years ago, published a groundbreaking (and taboo-breaking) Series on stillbirths. Its powerful mix of advocacy and hard data attracted more media attention than perhaps any other Series, and made waves on numerous levels, from the individual to the intergovernmental. Working closely with countrie
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Sarmila Mazumder PhD Sunita Taneja PhD Nita Bhandari PhD
2019-06-11
Sarmila Mazumder PhD, Sunita Taneja PhD, Nita Bhandari PhD (Centre for Health Research and Development, Society for Applied Studies, New Delhi, India). Emily R Smith MPH (Department ll-37 Global Health and Population, Harvard T H Chan School of Public Health, Boston, MA, USA), Masanja Honorati Ph
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Introduction Personalized medicine is the major goal of tran
2019-06-11
Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease daminozide and predict clinical outcome. However, to define a specific disease phenotype
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Un segundo aspecto que deber
2019-06-10
Un segundo aspecto que debería ser considerado para entender cabalmente por qué estas parentelas nobiliarias indígenas de Xolloco Acatla mostrarían una notable reluctancia sphingosine 1-phosphate receptor modulator relacionarse con los poderes de San Pablo, y, por el contrario, habrían exhibido una
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The study by Tripathy and colleagues yet again
2019-06-10
The study by Tripathy and colleagues yet again makes a convincing case for scaling up of participatory women\'s groups for learning and action to improve newborn survival in contextually comparable rural settings. Countries that do not have existing village-level functionaries who could act as facil
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Elderly patients especially those in excess of years of age
2019-06-10
Elderly patients, especially those in excess of 70 years of age, are often quite fragile; such fragility may be secondary to aging or comorbidity. In this “susceptible” patient population, the negative influence of ET-adverse events on patient adherence to a medication regimen can be elevated. This
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The congruence between BrS and ERS
2019-06-10
The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope
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br Conclusion Elevated levels of the myocardial damage
2019-06-10
Conclusion Elevated levels of the myocardial damage markers c-TNT and H-FABP were not found after ≤10J-DT (9J or 10J) in patients who underwent device implantation. Our findings confirm that minimally-invasive DT has an acceptable success rate. To prevent unnecessary myocardium damage, ≤10J-DT ma
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We are in the midst of a paradigm
2019-06-10
We are in the midst of a paradigm shift for antenatal and intrapartum care: from focusing mainly on coverage to also considering quality as an essential component of improving health systems, as stated in the WHO vision on quality of care and other efforts. For intrapartum care, poor quality at faci
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If the patient s coronary artery
2019-06-10
If the patient’s coronary artery is very close to the ablation target site, or if the origin of the VT/VPCs cannot be estimated by only the 12-lead ECG, for example, because of a severely deformed thorax or an alteration in the morphology of the VT, the CartoSound® system can be a useful tool for as
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Several mechanisms for cardiac involvement have
2019-06-10
Several mechanisms for cardiac involvement have been propounded as (1) direct cardiac involvement, (2) hematogenous spread, (3) lymphatic spread, (4) spreading from the venous system, such as the pulmonary vein or inferior vena cava. In cases of pericardium metastasis, most spreading routes result f
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The exhibited efficacies of bone targeting treatments in
2019-06-10
The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b
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br Conclusion The mm Jamshidi is feasible practical and
2019-06-10
Conclusion The 2mm Jamshidi is feasible, practical, and yields an adequate sample to assess bone structure and quality using microCT and histomorphometry in breast cancer patients. Additional samples are required to assess reproducibility, effect of bisphosphonates on bone quality and novel infor
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Prior case reports have described hematological remission in
2019-06-06
Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic ccr5 inhibitor on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we
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Initial bone marrow biopsy was inadequate in size for detail
2019-06-06
Initial bone marrow biopsy was inadequate in size for detailed examination and had severe crush artifact. The preserved focus of marrow showed hypercellularity with large, multinucleated, dysplastic megakaryocytes and megaloblastoid changes in erythroid series (Fig. 1B and C). There was no increase
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